340B Revenue Suite
Full-service 340B Third Party Administration — from HRSA eligibility through sustained program optimization. Performance-aligned, compliance-first, built for covered entities.
Get Started with RxLeverageFour service pillars covering the full 340B lifecycle — from initial registration to ongoing revenue optimization.
01
Registration & HRSA status maintenance
02
Pharmacy agreements & wholesaler setup
03
Audits, policies & program integrity
04
Analytics, claims recovery & growth
Pillar 01 — Eligibility
We manage the full lifecycle of your HRSA OPAIS registration — from initial qualification through ongoing maintenance.
Complete management of your 340B enrollment through the Office of Pharmacy Affairs Information System — from initial application to go-live.
Continuous monitoring and management of your 340B eligibility status, ensuring no lapses that could jeopardize program participation.
Systematic quarterly audits of the HRSA database to verify your entity information is accurate and current.
Verification and documentation that all grant-based and statutory qualifiers are satisfied and properly maintained for each entity type.
Pillar 02 — Implementation
Standing up the operational infrastructure — pharmacy agreements, wholesaler accounts, third-party contracts, and on-site pharmacy coordination.
Drafting, negotiation, and execution of contract pharmacy and in-house pharmacy service agreements tailored to your entity structure.
Account setup and credentialing with Cardinal Health, McKesson, and other major wholesalers — including 340B-specific pricing tiers.
Establishing and managing relationships with third-party administrators, split-billing software vendors, and claims processors.
Enrollment in Apexus and other prime vendor programs to secure the deepest sub-340B pricing on qualifying drug purchases.
Full operational support for standing up or optimizing an in-house pharmacy — from licensure to workflow design to opening day.
Pillar 03 — Compliance
Proactive compliance management — committee governance, policy frameworks, contract audits, and continuous monitoring against OPA guidance.
Facilitated 340B Oversight Committee sessions with structured agendas, compliance training, and documented governance records.
Creation and ongoing revision of 340B-specific P&Ps covering patient definition, mixed-use inventory, replenishment, and diversion controls.
Periodic reviews of all contract pharmacy, wholesaler, and TPA agreements to ensure compliance with 340B statutory and regulatory requirements.
Pillar 04 — Optimization & Support
Analytics, claims recovery, patient adherence, credentialing, and strategic growth across every dimension of your 340B operation.
Deep-dive reviews of provider encounters to maximize qualifying prescriptions captured under the 340B patient definition.
Identification and routing of eligible prescriptions that should be flowing through 340B channels but aren’t — closing the revenue gap.
Real-time performance dashboards tracking utilization rates, savings, capture percentages, and program health indicators.
Systematic identification and recovery of claims that qualify for 340B pricing but were processed at non-discounted rates.
Management of all Entity Service Provider uploads and data submissions required for program reporting and compliance.
Ongoing audits of wholesaler invoices against 340B ceiling prices to detect overcharges and recover overpayments.
Programs and strategies to improve medication adherence rates — driving better patient outcomes and sustained 340B utilization.
Structuring and managing affiliate site registrations, child site agreements, and multi-location program architectures.
Comprehensive 340B program health evaluations with actionable recommendations for revenue recovery and compliance hardening.
Long-term program strategy covering expansion opportunities, payer mix optimization, clinical revenue integration, and growth planning.
From your first conversation to sustained 340B revenue generation.
1
Entity type review, qualifying grants, payer mix, and program readiness.
2
HRSA OPAIS submission, qualifier verification, and entity configuration.
3
Pharmacy agreements, wholesaler credentialing, and compliance frameworks.
4
Go-live with KPI dashboards and hands-on support for 90 days.
∞
Continuous claims recovery, audits, and strategic expansion.
Identify missed 340B savings through non-captured claims analysis and wholesaler price verification.
Optimize TPA agreements for maximum margin capture through data-driven renegotiation and benchmarking.
Stay audit-ready with documented policies, committee governance, and continuous compliance monitoring.
Affiliate site agreements, child site registrations, and centralized program management across your network.
From HRSA eligibility verification to first prescription captured — full end-to-end program standup.
Drive 340B-eligible visit volume through targeted marketing, adherence programs, and referral network development.