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PrEP Injection Recall Worklist for Lapsed Patients

Carlos Rangel
PrEP Injection Recall Worklist for Lapsed Patients
Build a PrEP injection recall worklist that catches lapsed patients before they're lost. Cadence table, call scripts, and a 5-step weekly process.

Table of Contents

Last Updated: October 6, 2026

Why Automated Reminders Fail and What a Recall Worklist Fixes

An injection recall worklist is a weekly, human-owned list of patients who are due or overdue for an injectable PrEP dose, with a named staff member, a contact log, and an escalation rule for each row.

Automated reminders fail silently. A tickler fires in the EHR, a no-show text goes out, and then nothing happens when the patient ignores it. No one calls.

That gap matters because injectable PrEP only works on schedule. Apretude follows month 1, month 2, then every 2 months.

Miss a dose window and protection lapses. The patient rarely calls to say so.

Watch Out A reminder system with no named owner is not a recall system. When the tickler fires and no one acts, the patient simply disappears from the panel until they reappear with a new STI or a positive HIV test.

A worklist fixes this by making every overdue patient a visible, assigned task. Someone owns it. Someone logs the attempt. Someone escalates.

The Injectable PrEP Cadence You Are Recalling Against

The recall cadence depends on which injectable the patient is on. Get this table into your worklist logic before you build anything else.

Product Lead-In Maintenance Recall Trigger
Apretude (cabotegravir) Month 1, then month 2 Every 2 months 14 days before due date
Yeztugo (lenacapavir) Lead-in doses per label Every 6 months 30 days before due date
Oral PrEP (comparison) Daily Every 3 months visit 21 days before due date

Two things trip clinics up here. First, Apretude's second dose has a one-month window.

Second, oral PrEP patients on your panel still need quarterly HIV testing and STI screening.

Build the cadence into your tickler type, not into a spreadsheet someone updates by hand.

What Goes in a Patient Recall Worklist Template

A patient recall worklist template is the structured row format your team works from each week. It holds the minimum data needed to contact a patient, document the attempt, and close the loop.

Columns That Belong on Every Row

  • Patient name and MRN
  • Tickler type (for example, "PrEP injection due")
  • Product (Apretude, Yeztugo, oral)
  • Last dose date and next due date
Pro Tip Add an "attempt count" column and sort by it. Rows with zero attempts are the ones that quietly age out. Rows with two failed attempts need a different contact method, not a third identical call.

Keep PHI inside the EHR or your HIPAA-compliant CRM. Never export a worklist to a personal spreadsheet or email it to a shared inbox.

Five Steps to Run the Worklist Every Week

Running the worklist is a 60-minute weekly routine with a named owner. Here is the sequence.

A clinic staff member at a desk reviewing a printed worklist on a clipboard beside a laptop and a desk phone, warm office lighting, no visible patient names or screens readable
A clinic staff member at a desk reviewing a printed worklist on a clipboard beside a laptop and a desk phone, warm office lighting, no visible patient names or screens readable
  1. Pull the list. Run the EHR report for "PrEP injection due" and "HIV test overdue" ticklers. Anyone on a PrEP medication with no HIV test in 90 days belongs on it.
  2. Assign owners. Every row gets one name. Split by panel or by prescriber, not by whoever is free that day.
  3. Work the calls. Use the privacy-safe script below. Log every attempt with date, method, and outcome.
  4. Escalate after two attempts. Switch method, not volume. A portal message after two unanswered calls is a different channel, not a third call.
  5. Close the loop. Book the appointment before ending the call. Update worklist status to "booked" and confirm the CRM pipeline moved the patient.
Key Takeaway The worklist only works if the same person owns it every week. Rotating ownership is how overdue patients get lost between two well-meaning staff members.

A Patient Reactivation Call Script That Protects Privacy

A patient reactivation call script is a short, HIPAA-safe phone framework that invites the patient to a prevention visit without naming a test, a result, or a diagnosis on the call.

Here is the template. Fill in the bracketed fields.

"Hi, this is [name] calling from [clinic]. I'm reaching out because our records show you're due for a routine prevention visit. We'd like to get you scheduled at your convenience.

Rules that apply to every call:

  • Do not say the word "PrEP," a test name, or a result on the phone or in a voicemail.
  • Do not leave details on voicemail beyond a callback request.
  • Route any clinical question to the patient portal or the prescriber.
  • Offer bilingual outreach where the patient prefers Spanish or Haitian Creole.

If the patient asks why they are being called, the answer is a routine prevention visit. Nothing more.

Missed PrEP Injection Follow-Up: Clinical Safety and Re-Initiation

Missed PrEP injection follow-up is a clinical safety issue, not a scheduling one. When a dose window lapses, protection is not guaranteed, and the next step depends on how far past due the patient is and what their HIV status looks like today.

The worklist owner does not make the clinical call. The worklist owner makes sure the prescriber sees the row with enough information to make it.

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What the Worklist Must Surface Before the Prescriber Decides

  • Date of the last injection and the product (Apretude or Yeztugo)
  • Days past the due date, not just "overdue"
  • Most recent HIV test date and result, with the assay type (rapid vs. 4th-generation Ag/Ab with reflex RNA)
  • Whether the patient has had any potential exposure since the last dose
Watch Out Do not restart an injectable without a current HIV test on file. A positive or discordant result stops PrEP and triggers linkage to care. Skipping this step is a patient safety failure, not a scheduling shortcut.

Why the Apretude Dose 2 Window Is the One That Bites

Apretude runs month 1, month 2, then every 2 months.

When dose 2 slips past that window, the prescriber has to decide between resuming the injection schedule and restarting with an oral lead-in, depending on how long the gap is and the patient's exposure history.

A common pattern in programs we run: the recall trigger for dose 2 fires at 14 days before the due date, not on the due date.

The Testing Layer That Runs Alongside the Injection

Every injectable patient also needs HIV testing on the product's schedule, and that test is a separate tickler from the injection tickler. In our experience, clinics that merge the two into one row lose the testing signal when the injection gets rescheduled.

  • Rapid HIV at rooming satisfies the CDC 7-day rule, so the injection can go the same day.
  • 4th-generation Ag/Ab with reflex RNA confirms within 24-48 hours when the rapid is reactive or the history is unclear.
  • A positive or discordant result stops PrEP and triggers linkage, full stop.

Documentation Belongs in the Encounter, Not a Staff Case

Injection documentation, site, lot and expiration, HIV result, kit lot, often lives in a staff case note that no report can see. That is the same failure mode that produces an injection with no encounter, no note, and no charge. Put the documentation in the encounter and standardize an injection order set so the fields are not optional.

Key Takeaway The worklist owner owns contact and booking. The prescriber owns the re-initiation decision. Keep those roles separate, and make sure the row carries the HIV test date and result so the prescriber is not chasing the chart to make the call.

How CRM Pipelines Automate Rebooking and Outcome Tracking

A CRM pipeline turns the worklist from a weekly chore into an automatic rebooking engine. The injectable-PrEP pipeline runs on stages and triggers, not on memory.

The stages map to the clinical cadence:

  • Booked
  • Tested
  • Visit 2 at 1 month
  • Maintenance every 2 months

Each stage has a trigger. When a patient books, the pipeline advances. When a visit is missed, the pipeline flags the row for the worklist. When the patient is reached, the pipeline sets the next rebooking date automatically.

The Status Model That Closes a Row

A worklist row is not done when someone calls. It is done when the status changes to a state that removes it from the active queue. Use a small, fixed set:

Status Meaning Leaves the active queue?
Open No contact attempt logged yet No
Attempted One or more attempts logged, no booking No
Reached Patient answered and agreed to a plan Yes, once booked
Booked Appointment on the schedule Yes
Unreachable Two attempts, different channels, no response Yes, routed to prescriber
Closed Visit completed or patient declined Yes

What to Log on Every Attempt

  • Date and time of the attempt
  • Method (call, SMS, portal message, letter)
  • Outcome (no answer, voicemail, wrong number, reached, declined)
  • Staff member who made the attempt
  • Next action and date

Keep PHI inside the EHR or your HIPAA-compliant CRM. Never export a worklist to a personal spreadsheet or email it to a shared inbox.

The Metrics That Tell You It Is Working

A recall program that cannot report its own outcomes will not survive a staffing change. Track these weekly:

  • Contact rate: reached divided by total attempts
  • Re-engagement rate: booked divided by reached
  • Time overdue at booking: median days past due when the appointment is made
  • Kept-visit rate: completed visits divided by booked visits
  • Cost per kept visit by service line

In our experience, a scheduler working a clean list can realistically hit about 30 calls and 5 bookings per day per person. If the contact rate is high and the re-engagement rate is low, the problem is the offer or the script, not the list.

Where the Pipeline Sits in the Stack

This is where VaultStream, the HIPAA-compliant CRM in The Marketing Lab's Clinic Growth Suite, fits.

SMS consent matters here. A2P 10DLC registration needs separate consent checkboxes for customer-care versus promotional texts, STOP and HELP language, rates disclosure, and a no-purchase-condition clause in the terms.

Reporting should tie to kept appointments, not clicks. Never place PHI in ad platforms or analytics tools.

Key Takeaway The pipeline is only as good as its triggers. If a missed visit does not automatically create a worklist row, the recall program depends on someone noticing, and that is the failure mode you were trying to fix.

Frequently Asked Questions

How many times should a clinic attempt to contact a patient who missed an injection?

Two documented attempts, then escalate. In our experience the pattern that holds up is: attempt one within 48 hours of the missed date by phone, attempt two three to five days later through a second channel (portal message or SMS where consent exists), and if both go unanswered the row moves to an escalation queue owned by a named supervisor. Automated reminders alone fail silently because nobody calls when the tickler fires and the patient never responds. Log every attempt with date, channel, and outcome so the record shows a real effort rather than a single unanswered robocall.

What should staff document during PrEP injection recall outreach?

Log the contact attempt date and time, the channel used, who made the attempt, whether contact was made, and the patient's stated reason for missing the dose. Never record a test result, diagnosis, or medication name on a voicemail, in an SMS, or in a message a family member could see. PHI belongs in the patient portal or your HIPAA-compliant CRM, not in a call log visible to front desk staff. Worklist status should move through defined values (due, attempted, scheduled, kept, lost to follow-up) so a manager can see the queue at a glance.

How often are injectable PrEP follow-up visits scheduled?

Cabotegravir (Apretude) runs on a month 1, month 2, then every 2 months schedule after the oral lead-in, and the recall worklist should be built against that exact cadence rather than a generic 90-day tickler. Yeztugo follows a lead-in then every 6 months. Book the next injection before the patient leaves the room, and let the CRM pipeline rebook automatically at the clinical interval. A patient who is 30 days past an Apretude maintenance dose is a different clinical situation than one 30 days past an oral PrEP refill, so the worklist has to know which cadence applies.

What happens if a patient is late for an injectable PrEP dose?

Re-initiation rules depend on how far past the scheduled date the patient is, and for Apretude a dose 2 that slips past a month may require restarting the schedule rather than simply resuming. That is a clinical determination, so the worklist should flag the patient for the prescriber rather than have non-clinical staff decide. Confirm HIV status before any re-initiation, document the assessment, and link the patient back to care if the result is positive or discordant. In our experience the operational failure is not the clinical rule, it is that nobody owns the follow-up.

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